Terminliste
| 15.08.2021 | 1. runde | Bundesliga | Mainz | 1 - 0 | Leipzig | V sport1 | |
| 20.08.2021 | 2. runde | Bundesliga | Leipzig | 4 - 0 | Stuttgart | V sport1 | |
| 29.08.2021 | 3. runde | Bundesliga | Wolfsburg | 1 - 0 | Leipzig | V sport2 | |
| 11.09.2021 | 4. runde | Bundesliga | Leipzig | 1 - 4 | Bayern München | V sport1 | |
| 18.09.2021 | 5. runde | Bundesliga | Köln | 1 - 1 | Leipzig | V sport1 | |
| 25.09.2021 | 6. runde | Bundesliga | Leipzig | 6 - 0 | Hertha | V sport+ | |
| 02.10.2021 | 7. runde | Bundesliga | Leipzig | 3 - 0 | Bochum | V sport1 | |
| 16.10.2021 | 8. runde | Bundesliga | Freiburg | 1 - 1 | Leipzig | Viaplay | |
| 23.10.2021 | 9. runde | Bundesliga | Leipzig | 4 - 1 | Fürth | Viaplay | |
| 30.10.2021 | 10. runde | Bundesliga | Frankfurt | 1 - 1 | Leipzig | V sport1 | |
| 06.11.2021 | 11. runde | Bundesliga | Leipzig | 2 - 1 | Dortmund | V sport1 | |
| 20.11.2021 | 12. runde | Bundesliga | Hoffenheim | 2 - 0 | Leipzig | Viaplay | |
| 28.11.2021 | 13. runde | Bundesliga | Leipzig | 1 - 3 | Bayer Leverkusen | V sport2 | |
| 03.12.2021 | 14. runde | Bundesliga | Union Berlin | 2 - 1 | Leipzig | V sport+ | |
| 11.12.2021 | 15. runde | Bundesliga | Leipzig | 4 - 1 | M'gladbach | Viaplay | |
| 15.12.2021 | 16. runde | Bundesliga | Augsburg | 1 - 1 | Leipzig | Viaplay | |
| 18.12.2021 | 17. runde | Bundesliga | Leipzig | 0 - 2 | Bielefeld | Viaplay | |
| 08.01.2022 | 18. runde | Bundesliga | Leipzig | 4 - 1 | Mainz | Viaplay | |
| 15.01.2022 | 19. runde | Bundesliga | Stuttgart | 0 - 2 | Leipzig | Viaplay | |
| 23.01.2022 | 20. runde | Bundesliga | Leipzig | 2 - 0 | Wolfsburg | V sport2 | |
| 05.02.2022 | 21. runde | Bundesliga | Bayern München | 3 - 2 | Leipzig | V sport2 | |
| 11.02.2022 | 22. runde | Bundesliga | Leipzig | 3 - 1 | Köln | V sport1 | |
| 20.02.2022 | 23. runde | Bundesliga | Hertha | 1 - 6 | Leipzig | V sport2 | |
| 27.02.2022 | 24. runde | Bundesliga | Bochum | 0 - 1 | Leipzig | V sport1 | |
| 05.03.2022 | 25. runde | Bundesliga | Leipzig | 1 - 1 | Freiburg | Viaplay | |
| 13.03.2022 | 26. runde | Bundesliga | Fürth | 1 - 6 | Leipzig | V sport2 | |
| 20.03.2022 | 27. runde | Bundesliga | Leipzig | 0 - 0 | Frankfurt | V sport+ | |
| 02.04.2022 | 28. runde | Bundesliga | Dortmund | 1 - 4 | Leipzig | V sport1 | |
| 10.04.2022 | 29. runde | Bundesliga | Leipzig | 3 - 0 | Hoffenheim | V sport1 | |
| 17.04.2022 | 30. runde | Bundesliga | Bayer Leverkusen | 0 - 1 | Leipzig | V sport2 | |
| 23.04.2022 | 31. runde | Bundesliga | Leipzig | 1 - 2 | Union Berlin | V sport+ | |
| 02.05.2022 | 32. runde | Bundesliga | M'gladbach | 3 - 1 | Leipzig | V sport2 | |
| 08.05.2022 | 33. runde | Bundesliga | Leipzig | 4 - 0 | Augsburg | V sport2 | |
| 14.05.2022 | 34. runde | Bundesliga | Bielefeld | 1 - 1 | Leipzig | Viaplay |
Spillerstall
| Nr. | Navn | Posisjon | Alder | K | M |  |
 |
||
|---|---|---|---|---|---|---|---|---|---|
| 1 | Péter Gulácsi | Keeper | 31 | 33 | - | - | 1 | ||
| 13 | Phillipp Tschauner | Keeper | 36 | 1 | - | - | - | ||
| 31 | Josep Martinez | Keeper | 23 | 1 | - | - | - | ||
| 2 | Mohamed Simakan | Forsvar | 21 | 28 | 1 | - | 5 | ||
| 3 | Angeliño | Forsvar | 24 | 29 | 2 | - | 3 | ||
| 4 | Willi Orbán | Forsvar | 29 | 30 | 2 | - | 1 | ||
| 16 | Lukas Klostermann | Forsvar | 25 | 23 | - | - | 1 | ||
| 22 | Nordi Mukiele | Forsvar | 24 | 28 | 1 | - | 3 | ||
| 23 | Marcel Halstenberg | Forsvar | 30 | 8 | 1 | - | - | ||
| 32 | Josko Gvardiol | Forsvar | 19 | 29 | 2 | - | 7 | ||
| 35 | Solomon Bonnah | Forsvar | 18 | 1 | - | - | - | ||
| 39 | Benjamin Henrichs | Forsvar | 24 | 22 | 3 | - | 3 | ||
| 7 | Marcel Sabitzer | Midtbane | 27 | 2 | - | - | 1 | ||
| 8 | Amadou Haidara | Midtbane | 23 | 20 | 3 | - | 2 | ||
| 10 | Emil Forsberg | Midtbane | 30 | 31 | 6 | - | 2 | ||
| 11 | Hee-chan Hwang | Midtbane | 25 | 2 | - | - | - | ||
| 14 | Tyler Adams | Midtbane | 22 | 24 | - | - | 5 | ||
| 17 | Dominik Szoboszlai | Midtbane | 21 | 31 | 6 | - | 2 | ||
| 26 | Ilaix Moriba | Midtbane | 18 | 2 | - | - | - | ||
| 27 | Konrad Laimer | Midtbane | 24 | 26 | 4 | - | 2 | ||
| 37 | Sidney Raebiger | Midtbane | 16 | 1 | - | - | - | ||
| 44 | Kevin Kampl | Midtbane | 31 | 28 | - | - | 4 | ||
| 45 | Mehmet Ibrahimi | Midtbane | 18 | 0 | - | - | - | ||
| 47 | Joscha Wosz | Midtbane | 19 | 1 | - | - | - | ||
| 9 | Yussuf Poulsen | Angrep | 27 | 25 | 6 | - | 2 | ||
| 18 | Christopher Nkunku | Angrep | 24 | 34 | 20 | - | 2 | ||
| 21 | Brian Brobbey | Angrep | 19 | 9 | - | - | - | ||
| 25 | Dani Olmo | Angrep | 23 | 19 | 3 | - | 2 | ||
| 33 | André Silva | Angrep | 26 | 33 | 11 | - | 1 | ||
| 38 | Hugo Novoa | Angrep | 18 | 8 | 1 | - | - | ||
| 41 | Fabrice Hartmann | Angrep | 20 | 0 | - | - | - | ||
| Domenico Tedesco | Trener | 36 | 0 | - | - | 2 | |||
| Jesse Marsch | Hovedtrener | 48 | 0 | - | - | 1 | |||
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Forkortelser:
K: Kamper
M: Mål
Røde kort
Gule kort
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